Via boing boing, science fiction affects the mainstream in all sorts of unexpected ways:
1. Robotics. This is probably the most well-known of these, since Isaac Asimov is famous for (among many other things) his three laws of robotics. Even so, I include it because it is one of the only actual sciences to have been first named in a science fiction story (”Liar!”, 1941). Asimov also named the related occupation (roboticist) and the adjective robotic.
2. Genetic engineering. The other science that received its name from a science fiction story, in this case Jack Williamson’s novel Dragon’s Island, which was coincidentally published in the same year as “Liar!” The occupation of genetic engineer took a few more years to be named, this time by Poul Anderson.
3. Zero-gravity/zero-g. A defining feature of life in outer space (sans artificial gravity, of course). The first known use of “zero-gravity” is from Jack Binder (better known for his work as an artist) in 1938, and actually refers to the gravityless state of the center of the Earth’s core. Arthur C. Clarke gave us “zero-g” in his 1952 novel Islands in the Sky.
The list continues at the Oxford University Press blog.