The above comic is by John Porcellino. I wanted to start with it just because I think the man and his art stand on its own -- but read on and delve deeper into this cartoonist whose art carves deep into the experience of living.
There are several books available that collect his work-- his King Cat Classix comprises most of his work from the beginning of his career up to issue 50, and Map of My Heart is pretty much all the material from the next several issues after that. Perfect Example is a graphic novel comprised of several linked stories about the year he graduated from high school. Drawn & Quarterly, a fantastic comics publisher out of Canada, has issued these great works. However, my favorite collection of his work is his Diary of a Mosquito Abatement Man from the small press La Mano.
By the way, if you happen to be near any of these spots (including the Triangle area of N.C. today!) you can catch John on his current tour.